What do the new ‘gay gen’ tell about sexual orientatn? | New Scientist

Contents:

• THERE IS NO ‘GAY GENE.’ THERE IS NO ‘STRAIGHT GENE.’ SEXUALY IS JT PLEX, STUDY NFIRMS
• THERE’S (STILL) NO GAY GENE
• THE 'GAY GENE' IS A TOTAL MYTH, MASSIVE STUDY CONCLUS
• WHY ARE PEOPLE GAY? GAY BY CHOICE OR IS BEG GAY GEIC?
• IS BEG GAY GEIC?
• WHY GAYS DON’T GO EXTCT
• THERE’S NO ONE ‘GAY GENE,’ BUT GEICS ARE LKED TO SAME-SEX BEHAVR, NEW STUDY SAYS
• THE 'GAY GENE' IS A MYTH BUT BEG GAY IS 'NATURAL,' SAY SCIENTISTS
• THERE’S NO EVINCE THAT A SGLE ‘GAY GENE’ EXISTS
• MANY GEN INFLUENCE SAME-SEX SEXUALY, NOT A SGLE ‘GAY GENE’
• NO ‘GAY GENE’: MASSIVE STUDY HOM ON GEIC BASIS OF HUMAN SEXUALY
• IS THERE A "GAY GENE"? MAJOR NEW STUDY SAYS NO
• WHAT DO THE NEW ‘GAY GEN’ TELL ABOUT SEXUAL ORIENTATN?

THERE IS NO ‘GAY GENE.’ THERE IS NO ‘STRAIGHT GENE.’ SEXUALY IS JT PLEX, STUDY NFIRMS

It is worth keepg md that this study only vers some typ of sexualy — gay, lbian and cis-straight — but don’t offer many sights to genr inty.

Humans have tried to unrstand human sexualy for centuri — and geics rearchers joed the ay the early 1990s after a seri of studi on tws suggted homosexualy ran fai. “As a teenager tryg to unrstand myself and unrstand my sexualy, I looked at the ter for “the gay gene” and obvly me across Xq28, ” said Fah Sathirapongsasuti, a study -thor and senr scientist at 23andMe, which he joked once led him to believe he hered his gayns om his mother.

THERE’S (STILL) NO GAY GENE

“We worried a lot about volunteer bias, ” said Bailey, whose rearch clus a wily publicized study on Xq28 and gay brothers om 2018. Sanrs llaborated wh Bailey on those earlier studi and said their work had always admted that there was no sgle “gay gene.

The rearchers had members of the same-sex muny review the study’s sign and language, and they adm that their termology and fns for gay, lbian and heterosexual do not reflect the full nature of the sexualy ntuum.

“[Our study] unrsr an important role for the environment shapg human sexual behavr and perhaps most importantly there is no sgle gay gene but rather the ntributn of many small geic effects sttered across the genome, ” Neale said.

THE 'GAY GENE' IS A TOTAL MYTH, MASSIVE STUDY CONCLUS

There is no one gene for beg gay, and though gen seem to play a role termg sexual orientatn and same-sex behavr, ’s small, plex, and anythg but termistic. “There is no sgle gay gene, but rather the ntributn of many small geic effects sttered across the genome, ” he emphasized.

“We know that smell has a strong tie to sexual attractn, but s lks to sexual behavrs are not clear, ” said -thor Andrea Ganna, an stctor at HMS and Massachetts General Hospal om the Instute for Molecular Medice study is part a rponse to gay, lbian, and bisexual people’s cursy about themselv, said Fah Sathirapongsasuti, a senr scientist at 23andMe and -thor on the study, who is himself gay. Michael Bronski, profsor of the practice media and activism wh the mtee on studi of women, genr, and sexualy, and thor of A Queer History of the Uned Stat, says the allure of a “gay gene” grew om the flourishg gay-rights movement the after the Stonewall rts 1969. Conservative opponents of the movement claimed that “homosexual acts are a choice, people choose to m them, or people are sced to the gay liftyle, ” he explas.

WHY ARE PEOPLE GAY? GAY BY CHOICE OR IS BEG GAY GEIC?

’77, then a rearcher at the Natnal Instut of Health, published rults showg a rrelatn between male homosexual behavr and a clter of gen, lled Xq28, at the tip of the X chromosome. Exactly which gene this clter may be volved has proven elive—the current study found no signifint associatn between the X chromosome and same-sex sexual behavr—but the ia that a “gay gene” might lie somewhere Xq28—or elsewhere—was ptivatg.

IS BEG GAY GEIC?

Zeke Stok, chief programs officer of the LGBTQ advocy anizatn GLAAD, ncurred an emailed statement: “This new study provis even more evince that beg gay or lbian is a natural part of human life, a ncln that has been drawn by rearchers and scientists time and aga. Others have warned that the search for a geic e would pathologize homosexualy the same way psychology did the twentieth century: efforts by psychoanalysts such as Irvg Bieber led to the cln of homosexualy the Amerin Psychiatric Associatn’s Diagnostic and Statistil Manual of Mental Disorrs until 1972.

As noted above, the gen that rrelated wh same-sex sexual behavr also rrelated wh willgns to take risks, a nnectn that might not hold up cultur where homosexualy is ls stigmatized and those who are ls risk tolerant would therefore feel more able to act openly. However, blogists have documented homosexual behavr more than 450 speci, argug that same-sex behavr is not an unnatural choice, and may fact play a val role wh populatns.

WHY GAYS DON’T GO EXTCT

The 2019 study is the latt a hunt for “gay gen” that began 1993, when Dean Hamer lked male homosexualy to a sectn of the X chromosome.

As the ease and affordabily of genome sequencg creased, addnal gene ndidat have emerged wh potential lks to homosexual behavr.

THERE’S NO ONE ‘GAY GENE,’ BUT GEICS ARE LKED TO SAME-SEX BEHAVR, NEW STUDY SAYS

So-lled genome-wi associatn studi intified a gene lled SLITRK6, which is active a bra regn lled the diencephalon that differs size between people who are homosexual or heterosexual. Gay uncl and nts, for example, are “helpers the nt” that help raise other fay members’ children to nurture the fay tree. ” For example, certa gen women help crease their fertily, but if the gen are exprsed a male, they predispose him toward homosexualy.

While there is no sgle “gay gene, ” there is overwhelmg evince of a blogil basis for sexual orientatn that is programmed to the bra before birth based on a mix of geics and prenatal ndns, none of which the fet choos. Yet some fear that such a fdg uld be mised “cure” homosexualy, and most rearch teams have shied away om tacklg the topic. They asked more than 477, 000 participants whether they had ever had sex wh someone of the same sex, and also qutns about sexual fantasi and the gree to which they intified as gay or straight.

“A lot of people want to unrstand the blogy of homosexualy, and science has lagged behd that human tert, ” says William Rice, an evolutnary geicist at the Universy of California, Santa Barbara, who also was not volved the work.

THE 'GAY GENE' IS A MYTH BUT BEG GAY IS 'NATURAL,' SAY SCIENTISTS

Natnal Cancer Instute and his lleagu published a paper suggtg that an area on the X chromosome lled Xq28 uld nta a “gay gene.

His study, which analysed the genom of 40 pairs of gay brothers, looked exclively at people who intified as homosexual.

Those who nsir beg gay a disadvantage life (which still is, certa societi), might regard gay people differently if they knew that beg gay was an hered tra, rather than a nsequence of life events, such as a particular type of upbrgg, or mixg wh certa sorts of iends or even a liberate cisn. The law also might take a different view those untri (aga, there are still many) which beg gay is a crimal offense.

THERE’S NO EVINCE THAT A SGLE ‘GAY GENE’ EXISTS

An early study claimed that if one pair of (male) intil tws (who have intil geic patterns) was gay, there was a 100 percent chance of the other one also beg gay. It was quickly shown that, fact, the real chance of two intil tws beg gay was around 40-50 percent, whereas was ls non-intil on, though still somewhat greater than the general populatn.

MANY GEN INFLUENCE SAME-SEX SEXUALY, NOT A SGLE ‘GAY GENE’

There was another, much smaller, group who said they were entirely gay (about 6 percent), and a stterg of even smaller numbers who claimed to be bisexual.

NO ‘GAY GENE’: MASSIVE STUDY HOM ON GEIC BASIS OF HUMAN SEXUALY

No dividual gene alone mak a person gay, lbian or bisexual; stead, thoands of gen likely fluence sexual orientatn, a massive new study of the genom of nearly half a ln people human societi and both sex, between 2% and 10% of people report engagg sex wh a member of the same sex, eher exclively or addn to sex wh a member of the oppose sex, the rearchers said. Related: 5 Myths About Gay People Debunked"Bee is a ntroversial topic, fundg has historilly been limed and recment of participants was difficult, " study -thor Fah Sathirapongsasuti, a senr scientist and putatnal blogist at the geic ttg pany 23andMe, told Live Science.

However, the fdg that there's no sgle gay gene do not mean that sexual orientatn is not geic or blogil, and is therefore a liftyle choice. 13 Facts on the History of Marriage51 Sultry Facts About Sex10 Milton Gay Rights HistoryOrigally published on Live Science. In other words, 5-10% of people experience same-sex sexual attractn or behavr; of urse, this don't speak to what mak people gay.

IS THERE A "GAY GENE"? MAJOR NEW STUDY SAYS NO

It very much appears that same-sex sexual attractn is not a choice but actg on is; so if you fe gay as the mere prence of same-sex attractn, then om everythg we unrstand, beg gay is not a choice.

If, on the other hand, you nsir someone to be gay only if they act on their same-sex attractn then beg gay n be nsired a choice pendg on an dividual's behavr. Whether science n ultimately prove the blogy of beg gay or not, 's important to support all adults their choic no matter how they intify. Homosexualy mal may be ed part by gen that n crease fertily femal, acrdg to a new fdgs may help solve the puzzle of why, if homosexualy is heredary, hasn't already disappeared om the gene pool, sce gay people are ls likely to reproduce than heterosexuals.

The scientists ed a puter mol to expla how two gen passed on through the maternal le uld produce this 2004 the rearchers studied about 200 Italian fai and found that the mothers, maternal nts and maternal grandmothers of gay men are more fecund, or uful, than average.

WHAT DO THE NEW ‘GAY GEN’ TELL ABOUT SEXUAL ORIENTATN?

"The rearchers tail their fdgs the June 18 issue of the journal PLoS this scenar turns out to be te, uld help expla the seemg paradox of heredary homosexualy.

Sce gay people are ls likely to reproduce than heterosexuals, many experts have wonred why, if homosexualy is ed by geic factors, wouldn't have been elimated om the gene pool if the same gen create both homosexualy men and creased fertily women, then any loss offsprg that e about om the mal would be ma up for by the femal of the fay. We found that sexually antagonistic selectn is operatg also our speci, and we found a very important tra, which is homosexualy.

While many rearchers now agree homosexualy is probably ed by a mixture of nature and nurture, they are still hard prsed to expla the if this sexually antagonistic geic system is at work, n only acunt for a portn of the overall of homosexualy men, Camper-Ciani said. "I thk 's almost beyond a doubt that gen have some fluence, " said Ray Blanchard, a rearcher at the Centre for Addictn and Mental Health Toronto, who studi the effect of birth orr predictg whether a male will be born homosexual.