There’s (Still) No Gay Gene | Harvard Magaze

Contents:

• THERE IS NO ‘GAY GENE.’ THERE IS NO ‘STRAIGHT GENE.’ SEXUALY IS JT PLEX, STUDY NFIRMS
• WHY ARE PEOPLE GAY? GAY BY CHOICE OR IS BEG GAY GEIC?
• WHAT DO THE NEW ‘GAY GEN’ TELL ABOUT SEXUAL ORIENTATN?
• IS BEG GAY GEIC?
• IS BEG GAY YOUR DNA? SCIENTISTS KEEP TRYG TO FD A GEIC BASIS FOR SEXUAL ORIENTATN
• THERE’S NO ONE ‘GAY GENE,’ BUT GEICS ARE LKED TO SAME-SEX BEHAVR, NEW STUDY SAYS
• THE 'GAY GENE' IS A MYTH BUT BEG GAY IS 'NATURAL,' SAY SCIENTISTS
• MANY GEN INFLUENCE SAME-SEX SEXUALY, NOT A SGLE ‘GAY GENE’
• THERE’S (STILL) NO GAY GENE

THERE IS NO ‘GAY GENE.’ THERE IS NO ‘STRAIGHT GENE.’ SEXUALY IS JT PLEX, STUDY NFIRMS

It is worth keepg md that this study only vers some typ of sexualy — gay, lbian and cis-straight — but don’t offer many sights to genr inty. Humans have tried to unrstand human sexualy for centuri — and geics rearchers joed the ay the early 1990s after a seri of studi on tws suggted homosexualy ran fai.

“As a teenager tryg to unrstand myself and unrstand my sexualy, I looked at the ter for “the gay gene” and obvly me across Xq28, ” said Fah Sathirapongsasuti, a study -thor and senr scientist at 23andMe, which he joked once led him to believe he hered his gayns om his mother. The rearchers had members of the same-sex muny review the study’s sign and language, and they adm that their termology and fns for gay, lbian and heterosexual do not reflect the full nature of the sexualy ntuum. “[Our study] unrsr an important role for the environment shapg human sexual behavr and perhaps most importantly there is no sgle gay gene but rather the ntributn of many small geic effects sttered across the genome, ” Neale said.

It very much appears that same-sex sexual attractn is not a choice but actg on is; so if you fe gay as the mere prence of same-sex attractn, then om everythg we unrstand, beg gay is not a choice.

WHY ARE PEOPLE GAY? GAY BY CHOICE OR IS BEG GAY GEIC?

If, on the other hand, you nsir someone to be gay only if they act on their same-sex attractn then beg gay n be nsired a choice pendg on an dividual's behavr. Whether science n ultimately prove the blogy of beg gay or not, 's important to support all adults their choic no matter how they intify. We have known for s that sexual orientatn is partly herable men, thanks to studi of fai which some people are straight and some people are gay.

WHAT DO THE NEW ‘GAY GEN’ TELL ABOUT SEXUAL ORIENTATN?

In 1993, geic variatns a regn on the X chromosome men were lked to whether they were heterosexual or homosexual, and 1995, a regn on chromosome 8 was intified. Grave’s disease is more mon gay than straight men, and some rearch suggts that gay men tend to be thner – which might possibly be a rult of thyroid overdrive.

The latt fdgs open the prospect to intifyg the whole pathway of gen volved both homosexual and heterosexual orientatn, says Dean Hamer at the US Natnal Instut of Health, who led the study that ppoted chromosome X back 1993. However, blogists have documented homosexual behavr more than 450 speci, argug that same-sex behavr is not an unnatural choice, and may fact play a val role wh populatns. The 2019 study is the latt a hunt for “gay gen” that began 1993, when Dean Hamer lked male homosexualy to a sectn of the X chromosome.

So-lled genome-wi associatn studi intified a gene lled SLITRK6, which is active a bra regn lled the diencephalon that differs size between people who are homosexual or heterosexual. ” For example, certa gen women help crease their fertily, but if the gen are exprsed a male, they predispose him toward homosexualy. While there is no sgle “gay gene, ” there is overwhelmg evince of a blogil basis for sexual orientatn that is programmed to the bra before birth based on a mix of geics and prenatal ndns, none of which the fet choos.

IS BEG GAY GEIC?

Scientists may have fally solved the puzzle of what mak a person gay, and how is passed om parents to their children.A group of scientists suggted Tuday that homosexuals get that tra om their oppose-sex parents: A lbian will almost always get the tra om her father, while a gay man will get the tra om his mother.The heredary lk of homosexualy has long been tablished, but scientists knew was not a strictly geic lk, bee there are many pairs of intil tws who have differg sexuali. Scientists om the Natnal Instute for Mathematil and Blogil Synthis say homosexualy seems to have an epigeic, not a geic lk.Long thought to have some sort of heredary lk, a group of scientists suggted Tuday that homosexualy is lked to epi-marks — extra layers of rmatn that ntrol how certa gen are exprsed. In homosexuals, the epi-marks aren't erased — they're passed om father-to-dghter or mother-to-son, explas William Rice, an evolutnary blogist at the Universy of California Santa Barbara and lead thor of the study."There is pellg evince that epi-marks ntribute to both the siary and dissiary of fay members, and n therefore feasibly ntribute to the observed faial herance of homosexualy and s low nrdance between [intil] tws," Rice not.Rice and his team created a mathematil mol that explas why homosexualy is passed through epi-marks, not geics.

IS BEG GAY YOUR DNA? SCIENTISTS KEEP TRYG TO FD A GEIC BASIS FOR SEXUAL ORIENTATN

Evolutnarily speakg, if homosexualy was solely a geic tra, scientists would expect the tra to eventually disappear bee homosexuals wouldn't be expected to reproduce.

But bee the epi-marks provi an evolutnary advantage for the parents of homosexuals: They protect fathers of homosexuals om unrexposure to ttosterone and mothers of homosexuals om overexposure to ttosterone while they are gtatn."The epi-marks protect fathers and mothers om excs or unrexposure to ttosterone — when they rry over to oppose-sex offsprg, n e the masculizatn of femal or the femizatn of mal," Rice says, which n lead to a child beg gay. Rice not that the markers are "highly variable" and that only strong epi-marks will rult a homosexual offsprg.Though scientists have long spected some sort of geic lk, Rice says studi attemptg to expla why people are gay have been few and far between."Most mastream blogists have shied away om studyg bee of the social stigma," he says. Well there are many exampl of homosexualy nature, 's very mon." Homosexual behavr has been observed black swans, pengus, sheep, and other animals, he says.Rice's mol still needs to be tted on real-life parent-offsprg pairs, but he says this epigeic lk mak more sense than any other explanatn, and that his team has mapped out a way for other scientists to tt their work."We've found a story that looks really good," he says.

Disvered: No sign of a gay gene, but homosexualy uld start the womb; childhood oby is gog down; that fish you're eatg probably isn't really fish; a new SARS to eak out about. Rearchers om UC Santa Barbara and Uppsala Universy found a blogil basis for same-sex attractn, lotg the origs of homosexualy the womb. Media attentn centred on the prospect of a prenatal tt for sexual orientatn, wh the Daily Mail nng the headle: 'Abortn hope after "gay gen" fdg'.

THERE’S NO ONE ‘GAY GENE,’ BUT GEICS ARE LKED TO SAME-SEX BEHAVR, NEW STUDY SAYS

However, that don't mean that science has intified a "gay gene" or anythg like —and some scientists have utned agast overterpretg the fdgs.

Regns on two chromosom seemed to differ the most between people who intified as gay and those who intified as straight, acrdg to a study published Scientific Reports on Thursday. "A mon scenar this kd of rearch is that you'll hear people e a sort of shorthand like 'the gay gene, ' which is not really accurate at all.

THE 'GAY GENE' IS A MYTH BUT BEG GAY IS 'NATURAL,' SAY SCIENTISTS

The sample was limed several ways: about 1, 000 gay men—which isn't that many people for this kd of study—were reced at events like gay pri paras and had their genom analyzed. Ined, the study really only showed that two thgs happened at the same time: the gene regns varied between the two groups of men and one set of the men reported beg gay.

""Even if a gene variant do show some rrelatn wh sexual orientatn, this do not mean that the gene is any way rponsible for beg gay, " he wrote.

MANY GEN INFLUENCE SAME-SEX SEXUALY, NOT A SGLE ‘GAY GENE’

Those who nsir beg gay a disadvantage life (which still is, certa societi), might regard gay people differently if they knew that beg gay was an hered tra, rather than a nsequence of life events, such as a particular type of upbrgg, or mixg wh certa sorts of iends or even a liberate cisn. An early study claimed that if one pair of (male) intil tws (who have intil geic patterns) was gay, there was a 100 percent chance of the other one also beg gay. It was quickly shown that, fact, the real chance of two intil tws beg gay was around 40-50 percent, whereas was ls non-intil on, though still somewhat greater than the general populatn.

THERE’S (STILL) NO GAY GENE

There was another, much smaller, group who said they were entirely gay (about 6 percent), and a stterg of even smaller numbers who claimed to be bisexual. The rearchers say that, although variatns the gen nnot predict whether a person is gay, the variants may partly fluence sexual Ganna, lead thor and European Molecular Blogy Laboratory group lear at the Instute of Molecular Medice Fland, said the rearch rerc the unrstandg that same-sex sexual behavr is simply “a natural part of our diversy as a speci. Some of the variants were rrelated wh same-sex sexual behavr men, others women, and some Vila, director of the Center for Geic Medice Rearch at Children’s Natnal Health System, said the study marks the end of “the simplistic ncept of the ‘gay gene.

Environmental effects may be a factor for some people; for stance, havg olr brothers creas the odds that younger brothers will be gay, which rearchers spect may have to do wh chang to the mother’s immune system rponse to the earlier Stok, chief programs officer for GLAAD, said a statement that the new rearch on the geics “provis even more evince that beg gay or lbian is a natural part of human life, a ncln that has been drawn by rearchers and scientists time and aga. This new rearch also renfirms the long tablished unrstandg that there is no nclive gree to which nature or nurture fluence how a gay or lbian person behav. In theory, humans and other animals who are exclively attracted to others of the same sex should be unlikely to produce many blogil children, so any gen that predispose people to homosexualy would rarely be passed on to future generatns.

Yet same-sex attractn is wispread humans, and rearch suggts that is partly a study of data om hundreds of thoands of people, rearchers have now intified geic patterns that uld be associated wh homosexual behavur, and showed how the might also help people to fd different-sex mat, and reproduce. The thors say their fdgs, published on 23 Augt Nature Human Behavur1, uld help to expla why gen that predispose people to homosexualy ntue to be passed down. Most of the participants were born durg a time when homosexualy was eher illegal or culturally taboo their untri, so many people who were attracted to others of the same sex might never have actually acted on their attractn, and uld therefore have end up the wrong group the Monk, an elogist and evolutnary blogist at Yale Universy New Haven, Connecticut, thks that the veats are so important that the paper n’t draw any real nclns about geics and sexual orientatn.