There’s (Still) No Gay Gene | Harvard Magaze

Contents:

• THERE IS NO ‘GAY GENE.’ THERE IS NO ‘STRAIGHT GENE.’ SEXUALY IS JT PLEX, STUDY NFIRMS
• NO ‘GAY GENE’: MASSIVE STUDY HOM ON GEIC BASIS OF HUMAN SEXUALY
• IS THERE A "GAY GENE"? MAJOR NEW STUDY SAYS NO
• THERE’S NO ONE ‘GAY GENE,’ BUT GEICS ARE LKED TO SAME-SEX BEHAVR, NEW STUDY SAYS
• SEARCH FOR 'GAY GEN' COM UP SHORT IN LARGE NEW STUDY
• WHAT DO THE NEW ‘GAY GEN’ TELL ABOUT SEXUAL ORIENTATN?
• WHY ARE PEOPLE GAY? GAY BY CHOICE OR IS BEG GAY GEIC?
• THE 'GAY GENE' IS A TOTAL MYTH, MASSIVE STUDY CONCLUS
• THERE’S (STILL) NO GAY GENE
• THERE’S NO EVINCE THAT A SGLE ‘GAY GENE’ EXISTS
• MANY GEN INFLUENCE SAME-SEX SEXUALY, NOT A SGLE ‘GAY GENE’
• THE 'GAY GENE' IS A MYTH BUT BEG GAY IS 'NATURAL,' SAY SCIENTISTS
• NO SGLE ‘GAY GENE’ TERM SAME-SEX SEXUAL BEHAVR, DNA ANALYSIS FDS
• IS THERE A “GAY GENE"?

THERE IS NO ‘GAY GENE.’ THERE IS NO ‘STRAIGHT GENE.’ SEXUALY IS JT PLEX, STUDY NFIRMS

It is worth keepg md that this study only vers some typ of sexualy — gay, lbian and cis-straight — but don’t offer many sights to genr inty. Humans have tried to unrstand human sexualy for centuri — and geics rearchers joed the ay the early 1990s after a seri of studi on tws suggted homosexualy ran fai.

NO ‘GAY GENE’: MASSIVE STUDY HOM ON GEIC BASIS OF HUMAN SEXUALY

“As a teenager tryg to unrstand myself and unrstand my sexualy, I looked at the ter for “the gay gene” and obvly me across Xq28, ” said Fah Sathirapongsasuti, a study -thor and senr scientist at 23andMe, which he joked once led him to believe he hered his gayns om his mother.

“We worried a lot about volunteer bias, ” said Bailey, whose rearch clus a wily publicized study on Xq28 and gay brothers om 2018. Sanrs llaborated wh Bailey on those earlier studi and said their work had always admted that there was no sgle “gay gene.

IS THERE A "GAY GENE"? MAJOR NEW STUDY SAYS NO

The rearchers had members of the same-sex muny review the study’s sign and language, and they adm that their termology and fns for gay, lbian and heterosexual do not reflect the full nature of the sexualy ntuum. “[Our study] unrsr an important role for the environment shapg human sexual behavr and perhaps most importantly there is no sgle gay gene but rather the ntributn of many small geic effects sttered across the genome, ” Neale said.

“There is no ‘gay gene’, ” says lead study thor Andrea Ganna, a geicist at the Broad Instute of MIT and Harvard Cambridge, and his lleagu also ed the analysis to timate that up to 25% of sexual behavur n be explaed by geics, wh the rt fluenced by environmental and cultural factors — a figure siar to the fdgs of smaller studi. There's no such thg as a sgle "gay gene" that driv a person's sexual behavr, nclus the largt geic study ever nducted on the issue.

"This new study provis even more evince that that beg gay or lbian is a natural part of human life, a ncln that has been drawn by rearchers and scientists time and aga, " said GLAAD Chief Programs Officer Zeke Stok. This new rearch also renfirms the long-tablished unrstandg that there is no nclive gree to which nature or nurture fluence how a gay or lbian person behav. "This reflects voic om the LGBTQ+ (lbian, gay, bisexual, transgenr, queer+) muny argug that a range of sexuali exist, " Mills wrote.

THERE’S NO ONE ‘GAY GENE,’ BUT GEICS ARE LKED TO SAME-SEX BEHAVR, NEW STUDY SAYS

The rearchers say that, although variatns the gen nnot predict whether a person is gay, the variants may partly fluence sexual Ganna, lead thor and European Molecular Blogy Laboratory group lear at the Instute of Molecular Medice Fland, said the rearch rerc the unrstandg that same-sex sexual behavr is simply “a natural part of our diversy as a speci. Some of the variants were rrelated wh same-sex sexual behavr men, others women, and some Vila, director of the Center for Geic Medice Rearch at Children’s Natnal Health System, said the study marks the end of “the simplistic ncept of the ‘gay gene. Environmental effects may be a factor for some people; for stance, havg olr brothers creas the odds that younger brothers will be gay, which rearchers spect may have to do wh chang to the mother’s immune system rponse to the earlier Stok, chief programs officer for GLAAD, said a statement that the new rearch on the geics “provis even more evince that beg gay or lbian is a natural part of human life, a ncln that has been drawn by rearchers and scientists time and aga.

This new rearch also renfirms the long tablished unrstandg that there is no nclive gree to which nature or nurture fluence how a gay or lbian person behav. In an terview, she said the study is further evince that prev reports of a "gay gene" on the X chromosome are wrong. And bee the rearchers didn't fd gene variants that rrelated wh a gradient of sexual behavr, she says, unrcuts Aled Ksey's s-old sle, which ranked people on a spectm of sexualy, om exclively heterosexual to exclively homosexual.

However, blogists have documented homosexual behavr more than 450 speci, argug that same-sex behavr is not an unnatural choice, and may fact play a val role wh populatns.

SEARCH FOR 'GAY GEN' COM UP SHORT IN LARGE NEW STUDY

The 2019 study is the latt a hunt for “gay gen” that began 1993, when Dean Hamer lked male homosexualy to a sectn of the X chromosome.

As the ease and affordabily of genome sequencg creased, addnal gene ndidat have emerged wh potential lks to homosexual behavr.

WHAT DO THE NEW ‘GAY GEN’ TELL ABOUT SEXUAL ORIENTATN?

So-lled genome-wi associatn studi intified a gene lled SLITRK6, which is active a bra regn lled the diencephalon that differs size between people who are homosexual or heterosexual. Gay uncl and nts, for example, are “helpers the nt” that help raise other fay members’ children to nurture the fay tree.

” For example, certa gen women help crease their fertily, but if the gen are exprsed a male, they predispose him toward homosexualy. While there is no sgle “gay gene, ” there is overwhelmg evince of a blogil basis for sexual orientatn that is programmed to the bra before birth based on a mix of geics and prenatal ndns, none of which the fet choos. We have known for s that sexual orientatn is partly herable men, thanks to studi of fai which some people are straight and some people are gay.

WHY ARE PEOPLE GAY? GAY BY CHOICE OR IS BEG GAY GEIC?

In 1993, geic variatns a regn on the X chromosome men were lked to whether they were heterosexual or homosexual, and 1995, a regn on chromosome 8 was intified. Alan Sanrs at North Shore Universy, Illois, and his team ppoted the gen by parg DNA om 1077 gay and 1231 straight men. Intertgly, this bra regn ntas the hypothalam, which was intified 1991 as differg size between gay and straight men.

THE 'GAY GENE' IS A TOTAL MYTH, MASSIVE STUDY CONCLUS

Grave’s disease is more mon gay than straight men, and some rearch suggts that gay men tend to be thner – which might possibly be a rult of thyroid overdrive. There have been studi suggtg that there is a geic element to homosexualy women, but more rearch has been done men, says Sanrs.

The latt fdgs open the prospect to intifyg the whole pathway of gen volved both homosexual and heterosexual orientatn, says Dean Hamer at the US Natnal Instut of Health, who led the study that ppoted chromosome X back 1993. In other words, 5-10% of people experience same-sex sexual attractn or behavr; of urse, this don't speak to what mak people gay.

While psychologil factors may crease the likelihood that someone is gay, no sgle factor is known to e homosexualy.

THERE’S (STILL) NO GAY GENE

It very much appears that same-sex sexual attractn is not a choice but actg on is; so if you fe gay as the mere prence of same-sex attractn, then om everythg we unrstand, beg gay is not a choice. If, on the other hand, you nsir someone to be gay only if they act on their same-sex attractn then beg gay n be nsired a choice pendg on an dividual's behavr.

THERE’S NO EVINCE THAT A SGLE ‘GAY GENE’ EXISTS

Whether science n ultimately prove the blogy of beg gay or not, 's important to support all adults their choic no matter how they intify. Those who nsir beg gay a disadvantage life (which still is, certa societi), might regard gay people differently if they knew that beg gay was an hered tra, rather than a nsequence of life events, such as a particular type of upbrgg, or mixg wh certa sorts of iends or even a liberate cisn.

The law also might take a different view those untri (aga, there are still many) which beg gay is a crimal offense. An early study claimed that if one pair of (male) intil tws (who have intil geic patterns) was gay, there was a 100 percent chance of the other one also beg gay.

It was quickly shown that, fact, the real chance of two intil tws beg gay was around 40-50 percent, whereas was ls non-intil on, though still somewhat greater than the general populatn.

MANY GEN INFLUENCE SAME-SEX SEXUALY, NOT A SGLE ‘GAY GENE’

There was another, much smaller, group who said they were entirely gay (about 6 percent), and a stterg of even smaller numbers who claimed to be bisexual. Firstly, they found very few gen whose variatns were rrelated wh beg gay, or even havg a sgle same-sex partner. No dividual gene alone mak a person gay, lbian or bisexual; stead, thoands of gen likely fluence sexual orientatn, a massive new study of the genom of nearly half a ln people human societi and both sex, between 2% and 10% of people report engagg sex wh a member of the same sex, eher exclively or addn to sex wh a member of the oppose sex, the rearchers said.

THE 'GAY GENE' IS A MYTH BUT BEG GAY IS 'NATURAL,' SAY SCIENTISTS

Related: 5 Myths About Gay People Debunked"Bee is a ntroversial topic, fundg has historilly been limed and recment of participants was difficult, " study -thor Fah Sathirapongsasuti, a senr scientist and putatnal blogist at the geic ttg pany 23andMe, told Live Science.

However, the fdg that there's no sgle gay gene do not mean that sexual orientatn is not geic or blogil, and is therefore a liftyle choice. 13 Facts on the History of Marriage51 Sultry Facts About Sex10 Milton Gay Rights HistoryOrigally published on Live Science. There is no one gene for beg gay, and though gen seem to play a role termg sexual orientatn and same-sex behavr, ’s small, plex, and anythg but termistic.

“There is no sgle gay gene, but rather the ntributn of many small geic effects sttered across the genome, ” he emphasized. “We know that smell has a strong tie to sexual attractn, but s lks to sexual behavrs are not clear, ” said -thor Andrea Ganna, an stctor at HMS and Massachetts General Hospal om the Instute for Molecular Medice study is part a rponse to gay, lbian, and bisexual people’s cursy about themselv, said Fah Sathirapongsasuti, a senr scientist at 23andMe and -thor on the study, who is himself gay.

NO SGLE ‘GAY GENE’ TERM SAME-SEX SEXUAL BEHAVR, DNA ANALYSIS FDS

Michael Bronski, profsor of the practice media and activism wh the mtee on studi of women, genr, and sexualy, and thor of A Queer History of the Uned Stat, says the allure of a “gay gene” grew om the flourishg gay-rights movement the after the Stonewall rts 1969. Conservative opponents of the movement claimed that “homosexual acts are a choice, people choose to m them, or people are sced to the gay liftyle, ” he explas.

’77, then a rearcher at the Natnal Instut of Health, published rults showg a rrelatn between male homosexual behavr and a clter of gen, lled Xq28, at the tip of the X chromosome.

IS THERE A “GAY GENE"?

Exactly which gene this clter may be volved has proven elive—the current study found no signifint associatn between the X chromosome and same-sex sexual behavr—but the ia that a “gay gene” might lie somewhere Xq28—or elsewhere—was ptivatg. Zeke Stok, chief programs officer of the LGBTQ advocy anizatn GLAAD, ncurred an emailed statement: “This new study provis even more evince that beg gay or lbian is a natural part of human life, a ncln that has been drawn by rearchers and scientists time and aga. Others have warned that the search for a geic e would pathologize homosexualy the same way psychology did the twentieth century: efforts by psychoanalysts such as Irvg Bieber led to the cln of homosexualy the Amerin Psychiatric Associatn’s Diagnostic and Statistil Manual of Mental Disorrs until 1972.

As noted above, the gen that rrelated wh same-sex sexual behavr also rrelated wh willgns to take risks, a nnectn that might not hold up cultur where homosexualy is ls stigmatized and those who are ls risk tolerant would therefore feel more able to act openly. “There is no gay gene, ” Ganna said, “but rather non-heterosexualy is fluenced by many ty-effect geic factors.

Some people who have had sex wh a same-sex partner don’t nsir themselv gay and aren’t exclively attracted to people of the same sex, Bailey says.