There’s (Still) No Gay Gene | Harvard Magaze

Contents:

• THERE IS NO ‘GAY GENE.’ THERE IS NO ‘STRAIGHT GENE.’ SEXUALY IS JT PLEX, STUDY NFIRMS
• THERE’S (STILL) NO GAY GENE
• CLIL STUDY CONFIRMS PEOPLE ARE NOT BLOGILLY “BORN GAY”
• NO SGLE GENE ASSOCIATED WH BEG GAY
• WHY ARE PEOPLE GAY? GAY BY CHOICE OR IS BEG GAY GEIC?
• MANY GEN INFLUENCE SAME-SEX SEXUALY, NOT A SGLE ‘GAY GENE’
• BEG GAY NOT A CHOICE: SCIENCE CONTRADICTS BEN CARSON

THERE IS NO ‘GAY GENE.’ THERE IS NO ‘STRAIGHT GENE.’ SEXUALY IS JT PLEX, STUDY NFIRMS

The study of nearly a half ln people clos the door on the bate around the existence of a so-lled “gay gene. It is worth keepg md that this study only vers some typ of sexualy — gay, lbian and cis-straight — but don’t offer many sights to genr inty. Humans have tried to unrstand human sexualy for centuri — and geics rearchers joed the ay the early 1990s after a seri of studi on tws suggted homosexualy ran fai.

THERE’S (STILL) NO GAY GENE

“As a teenager tryg to unrstand myself and unrstand my sexualy, I looked at the ter for “the gay gene” and obvly me across Xq28, ” said Fah Sathirapongsasuti, a study -thor and senr scientist at 23andMe, which he joked once led him to believe he hered his gayns om his mother. “We worried a lot about volunteer bias, ” said Bailey, whose rearch clus a wily publicized study on Xq28 and gay brothers om 2018. Sanrs llaborated wh Bailey on those earlier studi and said their work had always admted that there was no sgle “gay gene.

The rearchers had members of the same-sex muny review the study’s sign and language, and they adm that their termology and fns for gay, lbian and heterosexual do not reflect the full nature of the sexualy ntuum. “[Our study] unrsr an important role for the environment shapg human sexual behavr and perhaps most importantly there is no sgle gay gene but rather the ntributn of many small geic effects sttered across the genome, ” Neale said. However, blogists have documented homosexual behavr more than 450 speci, argug that same-sex behavr is not an unnatural choice, and may fact play a val role wh populatns.

CLIL STUDY CONFIRMS PEOPLE ARE NOT BLOGILLY “BORN GAY”

The 2019 study is the latt a hunt for “gay gen” that began 1993, when Dean Hamer lked male homosexualy to a sectn of the X chromosome. As the ease and affordabily of genome sequencg creased, addnal gene ndidat have emerged wh potential lks to homosexual behavr. So-lled genome-wi associatn studi intified a gene lled SLITRK6, which is active a bra regn lled the diencephalon that differs size between people who are homosexual or heterosexual.

NO SGLE GENE ASSOCIATED WH BEG GAY

Wh multiple gene ndidat beg lked to homosexualy, seemed highly unlikely that a sgle “gay” gene exists. Several hypoth have been advanced to expla how homosexualy n be beneficial perpetuatg faial gen.

Gay uncl and nts, for example, are “helpers the nt” that help raise other fay members’ children to nurture the fay tree. ” For example, certa gen women help crease their fertily, but if the gen are exprsed a male, they predispose him toward homosexualy. While there is no sgle “gay gene, ” there is overwhelmg evince of a blogil basis for sexual orientatn that is programmed to the bra before birth based on a mix of geics and prenatal ndns, none of which the fet choos.

There is no one gene for beg gay, and though gen seem to play a role termg sexual orientatn and same-sex behavr, ’s small, plex, and anythg but termistic. “There is no sgle gay gene, but rather the ntributn of many small geic effects sttered across the genome, ” he emphasized.

WHY ARE PEOPLE GAY? GAY BY CHOICE OR IS BEG GAY GEIC?

“We know that smell has a strong tie to sexual attractn, but s lks to sexual behavrs are not clear, ” said -thor Andrea Ganna, an stctor at HMS and Massachetts General Hospal om the Instute for Molecular Medice study is part a rponse to gay, lbian, and bisexual people’s cursy about themselv, said Fah Sathirapongsasuti, a senr scientist at 23andMe and -thor on the study, who is himself gay.

Sathirapongsasuti wasn’t the only one lookg to the putative “gay gene” for self-unrstandg or validatn. Michael Bronski, profsor of the practice media and activism wh the mtee on studi of women, genr, and sexualy, and thor of A Queer History of the Uned Stat, says the allure of a “gay gene” grew om the flourishg gay-rights movement the after the Stonewall rts 1969. Conservative opponents of the movement claimed that “homosexual acts are a choice, people choose to m them, or people are sced to the gay liftyle, ” he explas.

MANY GEN INFLUENCE SAME-SEX SEXUALY, NOT A SGLE ‘GAY GENE’

’77, then a rearcher at the Natnal Instut of Health, published rults showg a rrelatn between male homosexual behavr and a clter of gen, lled Xq28, at the tip of the X chromosome. Exactly which gene this clter may be volved has proven elive—the current study found no signifint associatn between the X chromosome and same-sex sexual behavr—but the ia that a “gay gene” might lie somewhere Xq28—or elsewhere—was ptivatg. Zeke Stok, chief programs officer of the LGBTQ advocy anizatn GLAAD, ncurred an emailed statement: “This new study provis even more evince that beg gay or lbian is a natural part of human life, a ncln that has been drawn by rearchers and scientists time and aga.

Others have warned that the search for a geic e would pathologize homosexualy the same way psychology did the twentieth century: efforts by psychoanalysts such as Irvg Bieber led to the cln of homosexualy the Amerin Psychiatric Associatn’s Diagnostic and Statistil Manual of Mental Disorrs until 1972. As noted above, the gen that rrelated wh same-sex sexual behavr also rrelated wh willgns to take risks, a nnectn that might not hold up cultur where homosexualy is ls stigmatized and those who are ls risk tolerant would therefore feel more able to act openly.

A clear geic lk would suggt that gay people are “born this way, ” as opposed to havg ma a liftyle choice.

BEG GAY NOT A CHOICE: SCIENCE CONTRADICTS BEN CARSON

Yet some fear that such a fdg uld be mised “cure” homosexualy, and most rearch teams have shied away om tacklg the topic. They asked more than 477, 000 participants whether they had ever had sex wh someone of the same sex, and also qutns about sexual fantasi and the gree to which they intified as gay or straight. Dpe the associatns, the thors say that the geic siari still nnot show whether a given dividual is gay.

“It’s the end of the ’gay gene, ’” says Eric Vila, a geicist at Children’s Natnal Health System Washgton, D.

“A lot of people want to unrstand the blogy of homosexualy, and science has lagged behd that human tert, ” says William Rice, an evolutnary geicist at the Universy of California, Santa Barbara, who also was not volved the work. Natnal Cancer Instute and his lleagu published a paper suggtg that an area on the X chromosome lled Xq28 uld nta a “gay gene. His study, which analysed the genom of 40 pairs of gay brothers, looked exclively at people who intified as homosexual.